1

Mass from Volume & Concentration

mass = concentration × volume × MW

2

Volume from Mass & Concentration

volume = mass / (concentration × MW)

3

Molarity from Mass & Volume

molarity = mass / (MW × volume)

4

Moles from Mass

moles = mass / MW

Common Molecular Weights

Buffers & Salts

Sugars

Detergents

Nucleotides

Reducing Agents

Other Reagents

Click a compound to autofill the MW field of the last focused calculator. For peptide or oligo MW, use our Peptide MW Calculator or Nucleotide MW Calculator.

ℹ️ Frequently Asked Questions

What is molarity?

Molarity (M) is the number of moles of solute per liter of solution. A 1 M solution contains 1 mole of substance dissolved in enough solvent to make exactly 1 liter total.

Molarity (M) = moles of solute / volume of solution (L)

Common sub-units: mM (10⁻³ M), μM (10⁻⁶ M), nM (10⁻⁹ M). Molarity is the standard unit for concentration in biological research.

How do I calculate the mass needed for a molar solution?

Multiply the desired molarity by the volume (in liters) and the molecular weight (g/mol):

mass (g) = molarity (M) × volume (L) × MW (g/mol)

For example, to make 100 mL of 10 mM NaCl (MW = 58.44 g/mol):
mass = 0.01 M × 0.1 L × 58.44 g/mol = 0.058 g = 58.4 mg. Use Calculator 1 above and select your preferred result unit.

What is the difference between molarity and molality?

Molarity (M) = moles per liter of solution. Molality (m) = moles per kilogram of solvent.

In dilute aqueous solutions they are nearly identical, but molality is preferred for colligative properties because it does not change with temperature. For most bench-side biology work, molarity is the standard.

How do I convert between molarity and mg/mL?

Molarity and mg/mL are related through molecular weight:

mg/mL = molarity (M) × MW (g/mol)

For example, a 1 mM solution of a 50 kDa protein is: 0.001 M × 50,000 g/mol = 50 mg/mL. For direct unit conversion, use our Concentration Converter.

Why does this calculator show 3 decimal places?

Three decimal places match the precision of standard laboratory pipettes. Most adjustable pipettes (P2 through P5000) resolve to 0.001 mL (= 1 μL) at best. Showing more digits would imply false precision that cannot be achieved in practice.

Use the unit dropdown next to each result to select your preferred display unit. The "auto" option selects the most readable unit automatically.

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